China is at the forefront of applying CRISPR, a revolutionary genome editing tool that’s speeding progress in agriculture, biomedicine, and animal models. This package of print and audio stories explores every facet of CRISPR in China, much of which remains underreported, as well as the complex issues surrounding the regulations, oversight, investment, ethics, intellectual property, and the law. Specific stories focus on agriculture, the first clinical trial of a CRISPR medical therapeutic, animal studies related to organ transplants, and embryo editing.
For many people, CRISPR plus China equals the biophysicist He Jiankui, who infamously used the genome editor last year to alter the DNA of two human embryos that would become twin girls.
What are the potential impacts of modifying genes in humans? Jon Cohen reports on Lulu and Nana, Chinese twins who were genetically modified to be HIV resistant.
Some people who know He and have spoken to Science contend it is time for a more open discussion of how the biophysicist formed his circle of confidants and how the larger circle of trust—the one between the scientific community and the public—broke down.
Chinese researchers are investigating CRISPR's genome editing applications in monkeys, pigs, dogs, and even people.
The Pulitzer Center's newsletter for the week of July 30, 2019.