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Ugandan Hospital Pioneers New Treatment for Hydrocephalus

Blessing and her mother traveled two days by bus to reach the CURE Children's Hospital in Mbale, Uganda, that has pioneered a new treatment for infant hydrocephalus, a life-threatening condition in which fluid accumulates in the brain. Image by Bridget Huber. Uganda, 2014.

Blessing rests in the ward at the CURE Children's Hospital in Mbale, Uganda. After being treated for hydrocephalus months ago, she has returned to the hospital because her head has not stopped growing. Image by Bridget Huber. Uganda, 2014.

Blessing, a South Sudanese child with infant hydrocephalus, rests at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

Blessing recovers from surgery at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

Kasolo, a baby boy with hydrocephalus and spina bifida, awaits surgery in his mother's arms at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

Surgeons come from all over the world to the CURE Children's Hospital in Mbale, Uganda, where doctors developed a new treatment for hydrocephalus, called endoscopic third ventriculostomy with choroid plexus cauterization, or ETV/CPC. Image by Bridget Huber. Uganda, 2014.

Dr. John Mugamba, a neurosurgeon and medical director of the CURE Children's Hospital in Mbale, Uganda, treats a child with infant hydrocephalus. Image by Bridget Huber. Uganda, 2014.

Dr. Ben Warf, an American neurosurgeon, developed a new technique for treating infant hydrocephalus while working at the CURE Children's Hospital in Mbale Uganda. Image by Bridget Huber. Uganda, 2014.

American neurosurgeon Ben Warf spent six years working at the CURE Children's Hospital in Mbale, Uganda, and still returns regularly. During his time here, he developed a new technique for treating infant hydrocephalus called endoscopic third ventriculostomy with choroid plexus cauterization. He has brought the technique back to the U.S., where he uses it at Boston Children's Hospital. Image by Bridget Huber. Uganda, 2014.

An endoscope lights a child's head from within during treatment for infant hydrocephalus at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

A child lies on the operating table after his head was swabbed with antiseptic fluid in preparation for brain surgery at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

Dr. John Mugamba, working with a British surgical resident, places a shunt in a child with infant hydrocephalus. Whenever possible, the hospital tries to do a procedure called an endoscopic third ventriculostomy with choroid plexus coagulation instead of a shunt because shunts are prone to failure and infection. But the surgery is not an option for patients with severe scarring in certain parts of the brain. Image by Bridget Huber. Uganda, 2014.

Rehema, a six-year-old girl, recovers from surgery to readjust her shunt at the CURE Children's Hospital. Image by Bridget Huber. Uganda, 2014.

A mother shaves her child's head in preparation for neurosurgery at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

A child recovers from neurosurgery at the CURE Children's Hospital in Mbale, Uganda. Image by Bridget Huber. Uganda, 2014.

George, a baby girl from South Sudan, is bathed by her mother at the CURE Children's Hospital in Mbale, Uganda. Her mother has tied strings around her wrists, ankles and belly to monitor her growth. Image by Bridget Huber. Uganda, 2014.

Prossy's son, Steven, was treated for infant hydrocephalus and spina bifida at the CURE Children's Hospital in Mbale, Uganda, several years ago. Steven can't walk and has outgrown his crutches, so his mother has to carry him. Prossy, a hairdresser, supports her three children alone since her husband abandoned the family. Image by Bridget Huber. Uganda, 2014.

When western donors and governments build hospitals and buy medicine for people in the developing world, we often think of it as altruism or a moral obligation. But these kinds of investments can spur innovations that improve the health of people in poor and rich countries alike. When American neurosurgeon Ben Warf went to work at the CURE Children's Hospital in Mbale, Uganda, he was shocked at the number of children who were coming in for treatment for hydrocephalus—a life-threatening accumulation of fluid in the brain that's typically caused by a congenital disorder or an infection. "It was like being in the middle of some sort of epidemic," he said.

At first, Warf treated the condition as he always had in the U.S., by placing a shunt, a plastic tube that drains fluid from the brain into the abdomen. Even in the U.S., however, shunts aren't a perfect solution. They're prone to failure and infection, which in the U.S. means high medical costs and stress for families. But in countries like Uganda, where there's little access to neurosurgical care, such failures can have much more serious consequences. So Warf developed an innovative treatment for hydrocephalus that, when successful, fixes the problem permanently. The technique, called endoscopic third ventriculostomy with choriod plexus cauterization, or ETV/CPC, combined two existing treatments and has shown good results. The hospital, now staffed by Ugandan neurosurgeons trained by Warf, treats hydrocephalus primarily with ETV/CPC, except when patients have brain scarring that makes the surgery impossible.

ETV/CPC is increasingly being used all over the world. Neurosurgeons from Africa, the U.S., Asia and elsewhere come to the hospital in Mbale to learn the technique. And it's being done at several hospitals in the U.S., including Boston Children's Hospital where Warf now works.